TargetMol

Itraconazole

Product Code:
 
TAR-T1011
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1011-50mg50mg£98.00
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TAR-T1011-100mg100mg£109.00
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TAR-T1011-200mg200mg£132.00
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TAR-T1011-500mg500mg£213.00
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This product comes from: United States.
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Further Information

Bioactivity:
Itraconazole is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.
CAS:
84625-61-6
Formula:
C35H38Cl2N8O4
Molecular Weight:
705.63
Pathway:
Autophagy; Microbiology/Virology; Metabolism; Stem Cells; GPCR/G Protein
Purity:
0.9997
SMILES:
CCC(C)n1ncn(-c2ccc(cc2)N2CCN(CC2)c2ccc(OC[C@H]3CO[C@@](Cn4cncn4)(O3)c3ccc(Cl)cc3Cl)cc2)c1=O
Target:
P45; Hedgehog/Smoothened; Antibiotic; Autophagy; Antifungal

References

1. Isoherranen N, et al. Drug Metab Dispos, 2004, 32(10), 1121-1131. 2. Kim J, et al. Cancer Cell, 2010, 17(4), 388-399. 3. Oakley KL, et al. Antimicrob Agents Chemother, 1997, 41(5), 1124-1126. 4. Zuckerman JM, et al. Infect Control Hosp Epidemiol, 1994, 15(6), 397-410. 5. Leyden J, et al. J Am Acad Dermatol, 1998, 38(5 Pt 3), S42-47. 6. Tsang C C, Tang J Y M, Ye H, et al. Rare/cryptic Aspergillus species infections and importance of antifungal susceptibility testing[J]. Mycoses. 2020, 63(12): 1283-1298. 7. Tsang C C, Chan K F, Chan W, et al. Hepatic phaeohyphomycosis due to a novel dematiaceous fungus, Pleurostoma hongkongense sp. nov., and importance of antifungal susceptibility testing[J]. Emerging Microbes & Infections. 2020: 1-53.