TargetMol

DT-061

Product Code:
 
TAR-T10060L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10060L-5mg5mg£301.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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TAR-T10060L-50mg50mg£1,364.00
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Quantity:
TAR-T10060L-100mg100mg£2,030.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
DT-061 is an orally bioavailable protein phosphatase 2A (PP2A) activator. It could be applied in the therapy of KRAS-mutant and MYC-driven tumorigenesis.
CAS:
1809427-19-7
Formula:
C25H23F3N2O5S
Molecular Weight:
520.52
Pathway:
Metabolism
Purity:
0.98
SMILES:
O[C@H]1[C@@H](CCC[C@@H]1N1c2ccccc2Oc2ccccc12)NS(=O)(=O)c1ccc(OC(F)(F)F)cc1
Target:
Phosphatase

References

1. Kauko O, et al. PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells. Sci Transl Med. 2018 Jul 18;10(450). pii: eaaq1093.