TargetMol

Diammonium Glycyrrhizinate

Product Code:
 
TAR-T0522
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T0522-20mg20mg£99.00
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Quantity:
TAR-T0522-1mL1 mL * 10 mM (in DMSO)£111.00
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Further Information

Bioactivity:
Diammonium glycyrrhizinate, an extensively used anti-inflammatory agent, is isolated from the licorice root. It is metabolized to glycyrrhetinic acid, which inhibits 11-β-hydroxysteroid dehydrogenase and other enzymes involved in the metabolism of corticosteroids. Therefore, glycyrrhizic acid, the main and sweet component of licorice, has been studied for its ability to cause hypermineralocorticoidism with potassium loss and sodium retention, edema, increased blood pressure, as well as inhibited the renin-angiotensin-aldosterone system.
CAS:
79165-06-3
Formula:
C42H68N2O16
Molecular Weight:
857.004
Pathway:
Metabolism
Purity:
0.9971
SMILES:
N.N.CC1(C)[C@H](CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O)O[C@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O)C(O)=O
Target:
Dehydrogenase

References

1. Jin J, et al. Food Chem Toxicol. 2014 Nov;73:95-104. 2. He W, Zhai X, Su J, et al. Antiviral Activity of Germacrone against Pseudorabies Virus in Vitro[J]. Pathogens. 2019, 8(4): 258. 3. Zhai X, Wang S, Zhu M, et al. Antiviral Effect of Lithium Chloride and Diammonium Glycyrrhizinate on Porcine Deltacoronavirus In Vitro[J]. Pathogens. 2019, 8(3): 144.