TargetMol

NF023 hexasodium

Product Code:
 
TAR-TP2272
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-TP2272-10mg10mg£338.00
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TAR-TP2272-50mg50mg£841.00
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This product comes from: United States.
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Further Information

Bioactivity:
P2X1 receptor antagonist
CAS:
104869-31-0
Formula:
C35H32N4Na6O21S6
Molecular Weight:
1174.95
Pathway:
Neuroscience|Membrane transporter/Ion channel
Purity:
0.98
SMILES:
[NaH].[NaH].[NaH].[NaH].[NaH].[NaH].OS(=O)(=O)c1cc(c2c(NC(=O)c3cccc(NC(=O)Nc4cccc(c4)C(=O)Nc4ccc(c5cc(cc(c45)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O)c3)ccc(c2c1)S(O)(=O)=O)S(O)(=O)=O
Target:
P2X Receptor

References

G Lambrecht, et al. Agonists and Antagonists Acting at P2X Receptors: Selectivity Profiles and Functional Implications. Naunyn Schmiedebergs Arch Pharmacol. 2000 Nov;362(4-5):340-50. F Soto, et al. Antagonistic Properties of the Suramin Analogue NF023 at Heterologously Expressed P2X Receptors. Neuropharmacology. 1999 Jan;38(1):141-9. M Silva-Ramos, et al. Activation of Prejunctional P2x2/3 Heterotrimers by ATP Enhances the Cholinergic Tone in Obstructed Human Urinary Bladders. J Pharmacol Exp Ther. 2020 Jan;372(1):63-72. M Freissmuth, et al. Suramin Analogues as Subtype-Selective G Protein Inhibitors. Mol Pharmacol. 1996 Apr;49(4):602-11.