TargetMol

Dimethyl DL-Glutamate (hydrochloride)

Product Code:
 
TAR-T7658
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7658-1g1g£94.00
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Quantity:
TAR-T7658-1mL1 mL * 10 mM (in DMSO)£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
Dimethyl DL-glutamate is a cell-permeant glutamic acid derivative that enhances insulin release in response to glucose in isolated islets and in animal models of diabetes.
CAS:
13515-99-6
Formula:
C7H14ClNO4
Molecular Weight:
211.64
Purity:
0.98
SMILES:
Cl.COC(=O)CC[C@H](N)C(=O)OC

References

Jes?s Cancelas, Mar?a L. Villanueva-Pe?acrrillo, Valverde I , et al. Potentiation and prolongation of the insulinotropic action of glucagon-like peptide 1 by methyl pyruvate or dimethyl ester ofl-glutamic acid in a type 2 diabetes animal model[J]. Endocrine, 2001, 16(2):113-116. Casimir M , Lasorsa F M , Rubi B , et al. Mitochondrial Glutamate Carrier GC1 as a Newly Identified Player in the Control of Glucose-stimulated Insulin Secretion[J]. Journal of Biological Chemistry, 2009, 284(37):25004-25014.