TargetMol

Oxyphenisatin acetate

Product Code:
 
TAR-T7311
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7311-10mg10mg£109.00
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TAR-T7311-1mL1 mL * 10 mM (in DMSO)£114.00
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TAR-T7311-25mg25mg£122.00
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TAR-T7311-50mg50mg£136.00
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TAR-T7311-100mg100mg£159.00
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This product comes from: United States.
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Further Information

Bioactivity:
Oxyphenisatin acetate inhibits the growth of the breast cancer cell lines MCF7, T47D, HS578T, and MDA-MB-468.
CAS:
115-33-3
Formula:
C24H19NO5
Molecular Weight:
401.41
Pathway:
Autophagy
Purity:
0.98
SMILES:
CC(=O)Oc1ccc(cc1)C1(C(=O)Nc2ccccc12)c1ccc(OC(C)=O)cc1
Target:
Autophagy

References

Uddin M K , Reignier S G , Coulter T , et al. Syntheses and antiproliferative evaluation of oxyphenisatin derivatives[J]. Bioorganic & Medicinal Chemistry Letters, 2007, 17(10):2854-2857. Morrison B L , Mullendore M E , Stockwin L H , et al. Oxyphenisatin acetate (NSC 59687) triggers a cell starvation response leading to autophagy, mitochondrial dysfunction, and autocrine TNF?-mediated apoptosis[J]. Cancer Medicine, 2013:n/a-n/a.