TargetMol

LAZABEMIDE

Product Code:
 
TAR-T5470
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5470-1mL1 mL * 10 mM (in DMSO)£108.00
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TAR-T5470-10mg10mg£111.00
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TAR-T5470-25mg25mg£157.00
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TAR-T5470-50mg50mg£217.00
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Quantity:
TAR-T5470-100mg100mg£290.00
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This product comes from: United States.
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Further Information

Bioactivity:
LAZABEMIDE(Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively).
CAS:
103878-84-8
Formula:
C8H10ClN3O
Molecular Weight:
199.64
Pathway:
Neuroscience; Metabolism
Purity:
0.98
SMILES:
NCCNC(=O)c1ccc(Cl)cn1
Target:
MAO; Monoamine Oxidase

References

Holford N H , Guentert T W , Dingemanse J , et al. Pharmacodynamics of lazabemide, a reversible and selective inhibitor of monoamine oxidase B.[J]. British Journal of Clinical Pharmacology, 1994, 37(6):553-557. Saura J, et al. Quantitative enzyme radioautography with 3H-Ro 41-1049 and 3H-Ro 19-6327 in vitro: localization and abundance of MAO-A and MAO-B in rat CNS, peripheral organs, and human brain. J Neurosci. 1992 May;12(5):1977-99.