TargetMol

Glycochenodeoxycholic Acid

Product Code:
 
TAR-T4588
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4588-5mg5mg£95.00
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TAR-T4588-10mg10mg£108.00
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TAR-T4588-1mL1 mL * 10 mM (in DMSO)£112.00
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TAR-T4588-25mg25mg£132.00
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TAR-T4588-50mg50mg£160.00
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TAR-T4588-100mg100mg£203.00
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Quantity:
TAR-T4588-200mg200mg£267.00
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TAR-T4588-500mg500mg£405.00
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This product comes from: United States.
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Further Information

Bioactivity:
Glycolithocholic acid is a glycine conjugate of lithocholic acid, a bile acid. It is increased in livers of mice that are fed diets supplemented with ursadeoxycholic acid. Glycolithocholic acid levels are decreased in lean mice treated with obestatin. Serum glycolithocholic acid levels increase with age in children.
CAS:
640-79-9
Formula:
C26H43NO5
Molecular Weight:
449.632
Pathway:
Metabolism; Apoptosis
Purity:
0.98
SMILES:
C[C@H](CCC(=O)NCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
Target:
Apoptosis; Endogenous Metabolite

References

Kuipers F, Derksen JP, Gerding A, Scherphof GL, Vonk RJ. Biliary lipid secretion in the rat. The uncoupling of biliary cholesterol and phospholipid secretion from bile acid secretion by sulfated glycolithocholic acid. Biochim Biophys Acta. 1987 Nov 21;922(2):136-44. Kuipers F, Hardonk MJ, Vonk RJ, van der Meer R. Bile secretion of sulfated glycolithocholic acid is required for its cholestatic action in rats. Am J Physiol. 1992 Feb;262(2 Pt 1):G267-73. Qiu Q, Guo G, Guo X, et al.P53 Deficiency Accelerate Esophageal Epithelium Intestinal Metaplasia Malignancy.Biomedicines.2023, 11(3): 882.