TargetMol

4-Octyl itaconate

Product Code:
 
TAR-T4580
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4580-50mg50mg£104.00
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Quantity:
TAR-T4580-1mL1 mL * 10 mM (in DMSO)£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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Further Information

Bioactivity:
4-Octyl Itaconate is a cell-permeable Itaconate derivative and an anti-inflammatory metabolite. Itaconate activates Nrf2 via alkylation of KEAP1.
CAS:
3133-16-2
Formula:
C13H22O4
Molecular Weight:
242.315
Pathway:
Immunology/Inflammation
Purity:
0.9982
SMILES:
CCCCCCCCOC(=O)CC(=C)C(O)=O
Target:
Nrf2

References

Mills EL, et al. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature. 2018 Apr 5;556(7699):113-117. Wang S J, Ye W, Li W Y, et al.Effects and mechanisms of Xiaochaihu Tang against liver fibrosis: An integration of network pharmacology, molecular docking and experimental validation.Journal of Ethnopharmacology.2022: 116053.