TargetMol

Ramosetron

Product Code:
 
TAR-T4562
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4562-1mL1 mL * 10 mM (in DMSO)£108.00
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TAR-T4562-10mg10mg£111.00
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TAR-T4562-25mg25mg£124.00
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TAR-T4562-50mg50mg£162.00
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TAR-T4562-100mg100mg£205.00
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TAR-T4562-200mg200mg£275.00
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Further Information

Bioactivity:
Ramosetron is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. It is believed to have higher potency and longer antiemetic action than other 1st generation 5-HT3 antagonists such as ondansetron. Ramosetron is also indicated for a treatment of "diarrhea-predominant irritable bowel syndrome in males". It is only licensed for use in Japan and selected Southeast Asian countries.
CAS:
132036-88-5
Formula:
C17H17N3O
Molecular Weight:
279.343
Pathway:
GPCR/G Protein; Neuroscience
Purity:
0.9898
SMILES:
Cn1cc(C(=O)[C@@H]2CCc3nc[nH]c3C2)c2ccccc12
Target:
5-HT Receptor

References

Suzuki T, Sugimoto M, Koyama H, Mashimo T, Uchida I: Inhibitory effect of glucocorticoids on human-cloned 5-hydroxytryptamine3A receptor expressed in xenopus oocytes. Anesthesiology. 2004 Sep;101(3):660-5.