TargetMol

IRE1 α kinase-IN-2

Product Code:
 
TAR-T38841
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38841-10mg10mg£670.00
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TAR-T38841-25mg25mg£1,299.00
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Quantity:
TAR-T38841-50mg50mg£2,062.00
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Quantity:
TAR-T38841-100mg100mg£3,267.00
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This product comes from: United States.
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Further Information

Bioactivity:
IRE1α kinase-IN-2 is a potent IRE1α kinase inhibitor, with an EC 50 of 0.82 μM. IRE1α kinase-IN-2 inhibits IRE1α kinase autophosphorylation (IC 50 =3.12 μM). IRE1α kinase-IN-2 inhibits XBP1 mRNA splicing in the WT cell lines.
CAS:
1414938-21-8
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Wang L, Perera BG, Hari SB, et al. Divergent allosteric control of the IRE1? endoribonuclease using kinase inhibitors. Nat Chem Biol. 2012;8(12):982-989.