TargetMol

W140 (trifluoroacetate salt)

Product Code:
 
TAR-T38336
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38336-5mg5mg£1,010.00
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TAR-T38336-50mg50mg£1,982.00
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Quantity:
TAR-T38336-100mg100mg£2,560.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Sphingosine-1-phosphate (S1P) is a bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It exerts its activity by binding to five distinct G protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8. W140 is an inactive enantiomer of W146, a selective S1P1 antagonist (Ki = 77 nM), that binds to the S1P1 receptor with a Ki of 4.6 μM (2a = W146; 2b = W140 in supplemental material). It exhibits no biological activity in vivo and can therefore serve as an effective control compound for experiments involving W146.
CAS:
909725-64-0
Formula:
C16H27N2O4P?CF3COOH
Molecular Weight:
456.4
Purity:
0.98
SMILES:
CCCCCCC1=CC=CC(NC([C@@H](N)CCP(O)(O)=O)=O)=C1.FC(F)(C(O)=O)F