TargetMol

CHIC35

Product Code:
 
TAR-T27004
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27004-5mg5mg£930.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27004-50mg50mg£1,821.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27004-100mg100mg£2,319.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
CHIC-35 is a selective deacetylase SIRT1 inhibitor.
CAS:
848193-72-6
Formula:
C14H15ClN2O
Molecular Weight:
262.74
Purity:
0.98
SMILES:
NC(=O)[C@H]1CCCCc2c1[nH]c1ccc(Cl)cc21

References

1. Lugrin J, Ciarlo E, Santos A, Grandmaison G, dos Santos I, Le Roy D, Roger T. The sirtuin inhibitor cambinol impairs MAPK signaling, inhibits inflammatory and innate immune responses and protects from septic shock. Biochim Biophys Acta. 2013 Jun;1833(6):1498-510. doi: 10.1016/j.bbamcr.2013.03.004. Epub 2013 Mar 13. PubMed PMID: 23499872. 2. Reverchon M, Rame C, Bunel A, Chen W, Froment P, Dupont J. VISFATIN (NAMPT) Improves In Vitro IGF1-Induced Steroidogenesis and IGF1 Receptor Signaling Through SIRT1 in Bovine Granulosa Cells. Biol Reprod. 2016 Mar;94(3):54. doi: 10.1095/biolreprod.115.134650. Epub 2016 Jan 20. PubMed PMID: 26792944.