TargetMol

Bromfenac sodium hydrate

Product Code:
 
TAR-T2403
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2403-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T2403-10mg10mg£111.00
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TAR-T2403-25mg25mg£125.00
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TAR-T2403-50mg50mg£149.00
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TAR-T2403-100mg100mg£201.00
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TAR-T2403-200mg200mg£273.00
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TAR-T2403-500mg500mg£435.00
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This product comes from: United States.
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Further Information

Bioactivity:
Bromfenac Sodium Sesquihydrate is the sodium salt form of bromfenac, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory activities. Upon ophthalmic administration, bromfenac binds to and inhibits the activity of cyclooxygenase II (COX II), an enzyme which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins (PG). By inhibiting PG formation, bromfenac is able to inhibit PG-induced inflammation, thereby preventing vasodilation, leukocytosis, disruption of the blood-aqueous humor barrier, an increase in vascular permeability and an increase in intraocular pressure (IOP).
CAS:
120638-55-3
Formula:
C30H28Br2N2Na2O9
Molecular Weight:
766.347
Pathway:
Neuroscience; Immunology/Inflammation
Purity:
0.9185
SMILES:
O.O.O.[Na+].[Na+].Nc1c(CC([O-])=O)cccc1C(=O)c1ccc(Br)cc1.Nc1c(CC([O-])=O)cccc1C(=O)c1ccc(Br)cc1
Target:
COX

References

1. Shimura M, Yasuda K. Br J Ophthalmol. 2015 Feb;99(2):215-9.