TargetMol

NU 9056

Product Code:
 
TAR-T23095
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
NU 9056 is an effective and selective inhibitor of KAT5 histone acetyltransferase with an IC50 of 2 ?M. NU 9056 blocks DNA damage response and inhibits protein acetylation in prostate cancer cell lines.
CAS:
1450644-28-6
Formula:
C6H4N2S4
Molecular Weight:
232.37
Pathway:
Chromatin/Epigenetic
Purity:
0.98
SMILES:
C1(SSC2=CC=NS2)=CC=NS1
Target:
Histone Acetyltransferase

References

1. Klotilda Narkaj, et al. Blocking H2A.Z Incorporation via Tip60 Inhibition Promotes Systems Consolidation of Fear Memory in Mice. eNeuro. 2018 Nov 8;5(5):ENEURO.0378-18.2018. 2. Kelly Coffey, et al. Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer. PLoS One. 2012;7(10):e45539.