TargetMol

Fluticasone furoate

Product Code:
 
TAR-T21404
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T21404-5mg5mg£95.00
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TAR-T21404-10mg10mg£109.00
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TAR-T21404-1mL1 mL * 10 mM (in DMSO)£113.00
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TAR-T21404-25mg25mg£138.00
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TAR-T21404-50mg50mg£182.00
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TAR-T21404-100mg100mg£229.00
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TAR-T21404-200mg200mg£306.00
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TAR-T21404-500mg500mg£470.00
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This product comes from: United States.
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Further Information

Bioactivity:
Fluticasone furoate is a synthetic trifluorinated corticosteroid derived from fluticasone with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflammatory, anti-asthmatic activity, and low systemic exposure. Fluticasone furoate can be used as a nasal spray for studies about allergic rhinitis treatment.
CAS:
397864-44-7
Formula:
C27H29F3O6S
Molecular Weight:
538.58
Pathway:
Endocrinology/Hormones
Purity:
0.9958
SMILES:
C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)c1ccco1)C(=O)SCF
Target:
Glucocorticoid Receptor

References

1. Alizadeh Z, et al. Asthma phenotypes and T-bet protein expression in cells treated with Fluticasone Furoate/Vilanterol. Pulm Pharmacol Ther. 2020 Feb;60:101886. 2. Giavina-Bianchi P, et al. Fluticasone furoate nasal spray in the treatment of allergic rhinitis. Ther Clin Risk Manag. 2008 Apr;4(2):465-72. 3. Albertson TE, Richards JR, Zeki AA. The combination of fluticasone furoate and vilanterol trifenatate in the management of asthma: clinical trial evidence and experience. Ther Adv Respir Dis. 2016 Feb;10(1):43-56. 4. Syed YY. Fluticasone furoate/vilanterol: a review of its use in patients with asthma. Drugs. 2015 Mar;75(4):407-18.