TargetMol

N1-Methylpseudouridine

Product Code:
 
TAR-T19459
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T19459-1mL1 mL * 10 mM (in DMSO)£95.00
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Quantity:
TAR-T19459-10mg10mg£102.00
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TAR-T19459-25mg25mg£135.00
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TAR-T19459-50mg50mg£173.00
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Quantity:
TAR-T19459-100mg100mg£226.00
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Quantity:
TAR-T19459-500mg500mg£455.00
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This product comes from: United States.
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Further Information

Bioactivity:
N1-Methylpseudouridine is a methylpseudouridine and enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density in mRNA.
CAS:
13860-38-3
Formula:
C10H14N2O6
Molecular Weight:
258.23
Purity:
0.9914
SMILES:
Cn1cc([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]c1=O

References

1. Svitkin YV, et al. N1-methyl-pseudouridine in mRNA enhances translation through eIF2?-dependent and independent mechanisms by increasing ribosome density. Nucleic Acids Res. 2017 Jun 2;45(10):6023-6036. 2. Andries O, et al. N(1)-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice. J Control Release. 2015 Nov 10;217:337-44.