TargetMol

JW 642

Product Code:
 
TAR-T15632
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
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CodeSizePrice
TAR-T15632-5mg5mg£98.00
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TAR-T15632-10mg10mg£115.00
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TAR-T15632-1mL1 mL * 10 mM (in DMSO)£116.00
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TAR-T15632-25mg25mg£158.00
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TAR-T15632-50mg50mg£229.00
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TAR-T15632-100mg100mg£367.00
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Quantity:
TAR-T15632-200mg200mg£511.00
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This product comes from: United States.
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Further Information

Bioactivity:
JW 642 is an effective inhibitor of monoacylglycerol lipase (MAGL) (IC50: 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively).
CAS:
1416133-89-5
Formula:
C21H20F6N2O3
Molecular Weight:
462.392
Pathway:
Metabolism
Purity:
0.9913
SMILES:
FC(F)(F)C(OC(=O)N1CCN(Cc2cccc(Oc3ccccc3)c2)CC1)C(F)(F)F
Target:
Lipase

References

1. Chang JW, et al. Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates. Chem Biol. 2012 May 25;19(5):579-88.