TargetMol

(±)-10-Hydroxycamptothecin

Product Code:
 
TAR-T1521
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1521-25mg25mg£116.00
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TAR-T1521-50mg50mg£136.00
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Further Information

Bioactivity:
(?)-10-Hydroxycamptothecin is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
CAS:
64439-81-2
Formula:
C20H16N2O5
Molecular Weight:
364.35
Pathway:
DNA Damage/DNA Repair
Purity:
0.9958
SMILES:
CCC1(c2c(COC1=O)c(=O)n1Cc3c(c1c2)nc1ccc(cc1c3)O)O
Target:
Topoisomerase

References

1. Zhang S, et al. AntiY Drugs. 2014 Jul;25(6):614-23.