TargetMol

Nampt-IN-3

Product Code:
 
TAR-T13792
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13792-5mg5mg£370.00
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TAR-T13792-50mg50mg£1,661.00
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Quantity:
TAR-T13792-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Nampt-IN-3 simultaneously inhibit nicotinamide phosphoribosyltransferase (NAMPT) and HDAC (IC50s of 31 nM and 55 nM, respectively).
CAS:
2121591-52-2
Formula:
C29H25N7O2
Molecular Weight:
503.566
Purity:
0.98
SMILES:
Nc1ccccc1NC(=O)c1ccc(Cn2cc(nn2)-c2ccc(cc2)C(=O)NCc2cccnc2)cc1

References

1. Dong G, et al. Small Molecule Inhibitors Simultaneously Targeting Cancer Metabolism and Epigenetics: Discovery of Novel Nicotinamide Phosphoribosyltransferase (NAMPT) and Histone Deacetylase (HDAC) Dual Inhibitors. J Med Chem. 2017 Oct 12;60(19):7965-7983.