TargetMol

Veledimex (S enantiomer)

Product Code:
 
TAR-T13294
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13294-5mg5mg£670.00
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TAR-T13294-50mg50mg£1,661.00
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Quantity:
TAR-T13294-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Veledimex S enantiomer is the S enantiomer of veledimex. Veledimex is an oral activator ligand for a proprietary gene therapy promoter system and CYP3A4/5 inhibitor.
CAS:
1093131-03-3
Formula:
C27H38N2O3
Molecular Weight:
438.612
Purity:
0.98
SMILES:
CCC[C@H](N(NC(=O)c1cccc(OC)c1CC)C(=O)c1cc(C)cc(C)c1)C(C)(C)C

References

1. Cai H, et al. Plasma Pharmacokinetics of Veledimex, a Small-Molecule Activator Ligand for a Proprietary Gene Therapy Promoter System, in Healthy Subjects. Clin Pharmacol Drug Dev. 2017 May;6(3):246-257. 2. John A. Barrett, INTRATUMORAL REGULATED EXPRESSION OF IL-12 AS A GENE THERAPY APPROACH TO TREATMENT OF GLIOMA. Neuro Oncol. 2015 Nov; 17(Suppl 5): v113.