TargetMol

Urolithin B

Product Code:
 
TAR-T13265
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13265-10mg10mg£103.00
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TAR-T13265-1mL1 mL * 10 mM (in DMSO)£107.00
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TAR-T13265-25mg25mg£131.00
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TAR-T13265-50mg50mg£170.00
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TAR-T13265-100mg100mg£229.00
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Further Information

Bioactivity:
Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs. Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK.?Urolithin B is also a regulator of skeletal muscle mass. Urolithin B has anti-inflammatory and antioxidant effects.
CAS:
1139-83-9
Formula:
C13H8O3
Molecular Weight:
212.204
Pathway:
Chromatin/Epigenetic; PI3K/Akt/mTOR signaling; Cytoskeletal Signaling; Metabolism; NF-κb; MAPK
Purity:
0.9964
SMILES:
Oc1ccc2c(c1)oc(=O)c1ccccc21
Target:
ERK; NF-κB; Akt; Endogenous Metabolite; JNK; AMPK

References

1. Lee G, et al. Anti-inflammatory and antioxidant mechanisms of urolithin B in activated microglia. Phytomedicine. 2019 Mar 1;55:50-57. 2. Rodriguez J, et al. Urolithin B, a newly identified regulator of skeletal muscle mass. J Cachexia Sarcopenia Muscle. 2017 Aug;8(4):583-597.