TargetMol

Mitotane

Product Code:
 
TAR-T1199
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1199-50mg50mg£95.00
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TAR-T1199-100mg100mg£104.00
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TAR-T1199-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T1199-200mg200mg£117.00
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TAR-T1199-500mg500mg£142.00
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This product comes from: United States.
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Further Information

Bioactivity:
Mitotane is a derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
CAS:
53-19-0
Formula:
C14H10Cl4
Molecular Weight:
320.03
Pathway:
Apoptosis; Neuroscience
Purity:
0.9975
SMILES:
ClC(Cl)C(c1ccc(Cl)cc1)c1ccccc1Cl
Target:
Apoptosis; AChR

References

1. Zatelli MC, et al. Endocrinology,2010, 151(6), 2453-2561. 2. Lin CW, et al. Toxicology,2012, 298(1-3), 14-23. 3. Germano A, et al. Mol Cell Endocrinol. 2014 Jan 25;382(1):1-7. 4. Martz F, et al. Res Commun Chem Pathol Pharmacol,1976, 13(1), 83-92.