TargetMol

ACHN-975 TFA

Product Code:
 
TAR-T10236
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10236-5mg5mg£334.00
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Quantity:
TAR-T10236-50mg50mg£1,219.00
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Quantity:
TAR-T10236-100mg100mg£1,813.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
ACHN-975 TFA is a selective LpxC inhibitor with a subnanomolar inhibitory. It is against a wide range of gram-negative bacterias with low MIC values (?1 μg/mL).
CAS:
1410809-37-8
Formula:
C22H24F3N3O6
Molecular Weight:
483.444
Purity:
0.98
SMILES:
OC(=O)C(F)(F)F.CC(C)(N)[C@H](NC(=O)c1ccc(cc1)C#CC#C[C@@H]1C[C@H]1CO)C(=O)NO

References

1. Kalinin DV, et al. Insights into the Zinc-Dependent Deacetylase LpxC: Biochemical Properties and Inhibitor Design. Curr Top Med Chem. 2016;16(21):2379-430. 2. Krause KM,et al. Potent LpxC Inhibitors with In Vitro Activity against Multidrug-Resistant Pseudomonas aeruginosa.Antimicrob Agents Chemother. 2019 Oct 22;63(11). pii: e00977-19.