TargetMol

Novobiocin Sodium

Product Code:
 
TAR-T0974
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T0974-1mL1 mL * 10 mM (in DMSO)£103.00
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TAR-T0974-25mg25mg£104.00
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TAR-T0974-50mg50mg£118.00
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TAR-T0974-100mg100mg£140.00
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This product comes from: United States.
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Further Information

Bioactivity:
Novobiocin binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin.
CAS:
1476-53-5
Formula:
C31H35N2NaO11
Molecular Weight:
634.614
Pathway:
Membrane transporter/Ion channel; DNA Damage/DNA Repair; Microbiology/Virology; Autophagy
Purity:
0.9928
SMILES:
[Na+].COC1C(OC(N)=O)C(O)C(Oc2ccc3c(O)c(NC(=O)c4ccc([O-])c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C
Target:
Potassium Channel; DNA gyrase; Topoisomerase; Antibacterial; Antibiotic; ABC; Autophagy

References

1. Marcu MG, et al. J Biol Chem, 2000, 275(47), 37181-37186. 2. Yun BG, et al. Biochemistry,2004, 43(25), 8217-8229. 3. Singh G, et al. Mol Biochem Parasitol,2005, 141(1), 57-69. 4. Luo XG, et al. IUBMB Life,2010, 62(3), 194-199. 5. Lupescu A, et al. Cell Physiol Biochem,2014, 33(3), 670-680.