TargetMol

Epothilone D

Product Code:
 
TAR-TQ0202
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TQ0202-5mg5mg£201.00
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TAR-TQ0202-1mL1 mL * 10 mM (in DMSO)£211.00
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TAR-TQ0202-25mg25mg£491.00
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Further Information

Bioactivity:
Epothilone D (KOS 862) is an effective microtubule stabilizer.
CAS:
189453-10-9
Formula:
C27H41NO5S
Molecular Weight:
491.69
Pathway:
Cytoskeletal Signaling
Purity:
0.98
SMILES:
CC1CCCC(C)=CCC(OC(=O)CC(O)C(C)(C)C(=O)C(C)C1O)C(C)=Cc1csc(C)n1
Target:
Microtubule Associated

References

Brunden KR, et al. Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy. J Neurosci. 2010 Oct 13;30(41):13861-6. Konner J, et al. Phase I clinical, pharmacokinetic, and pharmacodynamic study of KOS-862 (Epothilone D) in patients with advanced solid tumors and lymphoma. Invest New Drugs. 2012 Dec;30(6):2294-302.