TargetMol

MK-0812

Product Code:
 
TAR-TQ0182
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-TQ0182-5mg5mg£1,332.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TQ0182-50mg50mg£2,625.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TQ0182-100mg100mg£3,524.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
MK-0812 is an effective and specific CCR2 antagonist.
CAS:
624733-88-6
Formula:
C24H34F3N3O3
Molecular Weight:
469.549
Pathway:
Immunology/Inflammation; Microbiology/Virology
Purity:
0.98
SMILES:
COC1COCCC1NC1CCC(C1)(C(C)C)C(=O)N1CCc2ncc(cc2C1)C(F)(F)F
Target:
CCR

References

Sugiyama S, Yumimoto K, Fujinuma S, et al.Identification of effective CCR2 inhibitors for cancer therapy using humanized mice.The Journal of Biochemistry.2023: mvad086. Wisniewski T, et al. Assessment of chemokine receptor function on monocytes in whole blood: In vitro and ex vivo evaluations of a CCR2 antagonist.J Immunol Methods. 2010 Jan 31;352(1-2):101-10. Min SH, et al. Pharmacological targeting reveals distinct roles for CXCR2/CXCR1 and CCR2 in a mouse model of arthritis.Biochem Biophys Res Commun. 2010 Jan 1;391(1):1080-6.