TargetMol

Dexpramipexole

Product Code:
 
TAR-TQ0175
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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TAR-TQ0175-5mg5mgEnquire
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  • Further Information
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Further Information

Bioactivity:
Dexpramipexole (KNS-760704, R-(+)-Pramipexole) is a neuroprotective agent and weak non-ergoline dopamine agonist.
CAS:
104632-28-2
Formula:
C10H17N3S
Molecular Weight:
211.33
Pathway:
GPCR/G Protein; Neuroscience
Purity:
0.98
SMILES:
CCCN[C@@H]1CCc2nc(N)sc2C1
Target:
Dopamine Receptor

Documents

References

Alavian KN, Dworetzky SI, Bonanni L, et al. Effects of dexpramipexole on brain mitochondrial conductances and cellular bioenergetic efficiency. Brain Res. 2012 Mar 29;1446:1-11. Bozik ME, Mather JL, Kramer WG, et al. Safety, tolerability, and pharmacokinetics of KNS-760704 (dexpramipexole) in healthy adult subjects. J Clin Pharmacol. 2011 Aug;51(8):1177-85. Cudkowicz M, Bozik ME, Ingersoll EW, et al. The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis. Nat Med. 2011 Nov 20;17(12):1652-6.