TargetMol

Zoliflodacin

Product Code:
 
TAR-TQ0063
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TQ0063-1mg1mg£161.00
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TAR-TQ0063-5mg5mg£290.00
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TAR-TQ0063-1mL1 mL * 10 mM (in DMSO)£306.00
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TAR-TQ0063-10mg10mg£417.00
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TAR-TQ0063-25mg25mg£646.00
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TAR-TQ0063-50mg50mg£863.00
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TAR-TQ0063-100mg100mg£1,171.00
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TAR-TQ0063-500mg500mg£2,263.00
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This product comes from: United States.
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Further Information

Bioactivity:
Zoliflodacin (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor. Zoliflodacin has potent in vitro antibacterial activity against Gram-positive and Gram-negative organisms, including S. aureus (MIC90: 0.25 μg/mL).
CAS:
1620458-09-4
Formula:
C22H22FN5O7
Molecular Weight:
487.444
Pathway:
Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
Purity:
0.9982
SMILES:
[H][C@]12[C@H](C)O[C@H](C)CN1c1c(CC22C(=O)NC(=O)NC2=O)cc2c(noc2c1F)N1[C@@H](C)COC1=O
Target:
DNA gyrase; DNA/RNA Synthesis; Topoisomerase; Antibacterial

References

Huband MD, et al. In vitro antibacterial activity of AZD0914, a new spiropyrimidinetrione DNA gyrase/topoisomerase inhibitor with potent activity against Gram-positive, fastidious Gram-Negative, and atypical bacteria. Antimicrob Agents Chemother. 2015 Jan;59(1):467-74.