TargetMol

1-HEXACOSANOL

Product Code:
 
TAR-TN6751
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN6751-50mg50mg£94.00
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Further Information

Bioactivity:
Hexacosanol activates AMPK and hepatic autophagy and inhibits SREBP2, resulting in hypocholesterolemic activities and improvement of hepatic steatosis.
CAS:
506-52-5
Formula:
C26H54O
Molecular Weight:
382.717
Pathway:
PI3K/Akt/mTOR signaling; Membrane transporter/Ion channel; Chromatin/Epigenetic
Purity:
0.98
SMILES:
CCCCCCCCCCCCCCCCCCCCCCCCCCO
Target:
NPC1L1; AMPK

References

Lee JH, Jia Y, Thach TT, Han Y, Kim B, Wu C, Kim Y, Seo WD, Lee SJ. Hexacosanol reduces plasma and hepatic cholesterol by activation of AMP-activated protein kinase and suppression of sterol regulatory element-binding protein-2 in HepG2 and C57BL/6J mice. Nutr Res. 2017 Jul;43:89-99. Saito M, Kinoshita Y, Satoh I, Shinbori C, Kono T, Hanada T, Uemasu J, Suzuki H, Yamada M, Satoh K. N-hexacosanol ameliorates streptozotocin-induced diabetic rat nephropathy. Eur J Pharmacol. 2006 Aug 21;544(1-3):132-7.