TargetMol

Euphohelioscopin A

Product Code:
 
TAR-TN5593
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN5593-5mg5mg£601.00
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Quantity:
TAR-TN5593-1mL1 mL * 10 mM (in DMSO)£609.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Euphohelioscopin A, an activator of protein kinase C (PKC), it inhibits proliferation and induces differentiation of the myeloid leukemia cell lines THP-1 and HL-60. Euphohelioscopin A has anti-inflammary activity, it exhibits moderate inhibitory activity on the release of cytokine TNF-α (IC50 = 23.7 ? 1.7 uM), IL-6 (IC50 = 46.1 ? 1.1 uM) and chemokine MCP-1 (IC50 = 33.7 ? 3.8 uM) in lipopolysaccharide (LPS) induced RAW 264.7 macrophages without notable cytotoxicity (IC50 > 80 uM).
CAS:
87064-61-7
Formula:
C30H42O6
Molecular Weight:
0
Purity:
0.98
SMILES:
CCCC=CC=CC(=O)O[C@@H]1C[C@H]2[C@@H](C=C(C)C(=O)[C@]3(C[C@@H](C)[C@H](O)[C@@H]3C=C1/C)OC(C)=O)C2(C)C