TargetMol

4-Methyldaphnetin

Product Code:
 
TAR-TJS0315
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TJS0315-5mg5mg£102.00
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TAR-TJS0315-1mL1 mL * 10 mM (in DMSO)£105.00
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TAR-TJS0315-10mg10mg£122.00
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TAR-TJS0315-25mg25mg£161.00
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TAR-TJS0315-50mg50mg£222.00
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TAR-TJS0315-100mg100mg£298.00
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Further Information

Bioactivity:
1. 4-Methyldaphnetin is a potent inhibitor (low micromolar) of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radicals, but may be pro-oxidant (enhancing generation of hydroxyl radicals) in the presence of free iron ions.2. 4-Methyldaphnetin inhibits the proinflammatory 5-lipoxygenase enzyme at micromolar concentrations.
CAS:
2107-77-9
Formula:
C10H8O4
Molecular Weight:
192.17
Pathway:
Apoptosis; Metabolism
Purity:
0.9957
SMILES:
Cc1cc(=O)oc2c(O)c(O)ccc12
Target:
Apoptosis; Lipoxygenase

References

Hoult J R S , Miguel Pay??. Pharmacological and biochemical actions of simple coumarins: Natural products with therapeutic potential[J]. General Pharmacology the Vascular System, 1996, 27(4):713-722.