TargetMol

Atraric acid

Product Code:
 
TAR-TCS1372
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TCS1372-500mg500mg£103.00
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Quantity:
TAR-TCS1372-1mL1 mL * 10 mM (in DMSO)£107.00
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Further Information

Bioactivity:
Atraric acid derivatives as a new chemical lead structure for novel therapeutic compounds as AR antagonists, that can be used for prophylaxis or treatment of prostatic diseases. It inhibits PTP1B activity in a dose-dependent manner with IC50 values of 51.5 uM, suggest that atraric acid has potential to treat diabetes.
CAS:
4707-47-5
Formula:
C10H12O4
Molecular Weight:
196.202
Pathway:
Metabolism; Endocrinology/Hormones
Purity:
0.9927
SMILES:
COC(=O)c1c(C)cc(O)c(C)c1O
Target:
Phosphatase; Androgen Receptor

References

Computational and functional analysis of the androgen receptor antagonist atraric acid and its derivatives. Anticancer Agents Med Chem. 2013 Jun;13(5):801-10. PTP1B inhibitory secondary metabolites from the Antarctic lichen Lecidella carpathica. Mycology An International Journal on Fungal Biology, 2011, 2(1):18-23.