TargetMol

δ-secretase inhibitor 11

Product Code:
 
TAR-T9713
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9713-5mg5mg£95.00
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Quantity:
TAR-T9713-1mL1 mL * 10 mM (in DMSO)£102.00
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TAR-T9713-10mg10mg£105.00
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TAR-T9713-25mg25mg£148.00
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TAR-T9713-50mg50mg£205.00
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Quantity:
TAR-T9713-100mg100mg£270.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.
CAS:
842964-18-5
Formula:
C10H12N4O2
Molecular Weight:
220.232
Pathway:
Neuroscience; Proteases/Proteasome; Apoptosis
Purity:
0.98
SMILES:
Nc1ccc(N2CCOCC2)c2nonc12
Target:
Beta Amyloid; Caspase

References

Ju Wang, et al. Pharmacological inhibition of asparaginyl endopeptidase by ?-secretase inhibitor 11 mitigates Alzheimer?s disease-related pathologies in a senescence-accelerated mouse model. Translational Neurodegeneration volume 10, Article number: 12 (2021).