TargetMol

Diflapolin

Product Code:
 
TAR-T8844
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8844-1mL1 mL * 10 mM (in DMSO)£122.00
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TAR-T8844-5mg5mg£122.00
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TAR-T8844-10mg10mg£161.00
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TAR-T8844-25mg25mg£266.00
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TAR-T8844-50mg50mg£396.00
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TAR-T8844-100mg100mg£544.00
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TAR-T8844-500mg500mg£1,099.00
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This product comes from: United States.
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Further Information

Bioactivity:
Diflapolin is a highly active dual 5-lipoxygenase-activating protein (FLAP)/soluble epoxide hydrolase (sEH) inhibitor with marked anti-inflammatory efficacy and high target selectivity.
CAS:
724453-98-9
Formula:
C22H17Cl2N3O2S
Molecular Weight:
458.36
Pathway:
Metabolism; ; Immunology/Inflammation
Purity:
0.9923
SMILES:
Cc1cc(OCc2nc3ccccc3s2)ccc1NC(=O)Nc1ccc(Cl)c(Cl)c1
Target:
FLAP; Epoxide Hydrolase

References

Garscha U, Romp E, Pace S, et al. Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase. Sci Rep. 2017;7(1):9398. Published 2017 Aug 24. doi:10.1038/s41598-017-09795-w