TargetMol

PU02

Product Code:
 
TAR-T8445
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8445-5mg5mg£115.00
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Quantity:
TAR-T8445-1mL1 mL * 10 mM (in DMSO)£119.00
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Quantity:
TAR-T8445-10mg10mg£148.00
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Quantity:
TAR-T8445-25mg25mg£222.00
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Quantity:
TAR-T8445-50mg50mg£349.00
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Quantity:
TAR-T8445-100mg100mg£516.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
PU-02 is a potent and selective antagonist of 5-HT3 receptor.
CAS:
313984-77-9
Formula:
C16H12N4S
Molecular Weight:
292.36
Pathway:
Apoptosis; GPCR/G Protein; Neuroscience
Purity:
0.9965
SMILES:
C(Sc1ncnc2[nH]cnc12)c1cccc2ccccc12
Target:
Apoptosis; 5-HT Receptor

References

Trattnig S M , Harpsoe K , Thygesen S B , et al. Discovery of a Novel Allosteric Modulator of 5-HT3 Receptors: INHIBITION AND POTENTIATION OF CYS-LOOP RECEPTOR SIGNALING THROUGH A CONSERVED TRANSMEMBRANE INTERSUBUNIT SITE[J]. Journal of Biological Chemistry, 2012, 287(30):25241-25254.