TargetMol

GKT136901

Product Code:
 
TAR-T8408
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8408-5mg5mg£104.00
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Quantity:
TAR-T8408-1mL1 mL * 10 mM (in DMSO)£107.00
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Quantity:
TAR-T8408-10mg10mg£120.00
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TAR-T8408-25mg25mg£163.00
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Quantity:
TAR-T8408-50mg50mg£203.00
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Quantity:
TAR-T8408-100mg100mg£253.00
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Quantity:
TAR-T8408-200mg200mg£347.00
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This product comes from: United States.
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Further Information

Bioactivity:
GKT136901 is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite
CAS:
955272-06-7
Formula:
C19H15ClN4O2
Molecular Weight:
366.81
Pathway:
Immunology/Inflammation; Metabolism
Purity:
0.9829
SMILES:
Cc1n(Cc2ccccn2)c(=O)cc2[nH]n(-c3ccccc3Cl)c(=O)c12
Target:
NADPH-oxidase; NADPH

References

Fiona Augsburger , Aleksandra Filippova , Delphine Rasti.Pharmacological Characterization of the Seven Human NOX Isoforms and Their Inhibitors.Redox Biol. 2019 Sep;26:101272. S Schildknecht, A Weber, H R Gerding.The NOX1/4 Inhibitor GKT136901 as Selective and Direct Scavenger of Peroxynitrite.Curr Med Chem. 2014;21(3):365-76.