TargetMol

Mitochonic acid 5

Product Code:
 
TAR-T8366
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8366-1mg1mg£106.00
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TAR-T8366-5mg5mg£148.00
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TAR-T8366-1mL1 mL * 10 mM (in DMSO)£164.00
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TAR-T8366-10mg10mg£222.00
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TAR-T8366-25mg25mg£374.00
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TAR-T8366-50mg50mg£527.00
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Quantity:
TAR-T8366-100mg100mg£725.00
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This product comes from: United States.
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Further Information

Bioactivity:
Mitochonic acid 5 is a derivative of the plant hormone indole-3-acetic acid. Mitochonic acid 5 binds mitochondria and ameliorates renal tubular and cardiac myocyte damage.It has been shown to improve survival of fibroblasts from patients with mitochondrial diseases.
CAS:
1354707-41-7
Formula:
C18H13F2NO3
Molecular Weight:
329.303
Pathway:
Metabolism
Purity:
0.9991
SMILES:
OC(=O)C(CC(=O)c1ccc(F)cc1F)c1c[nH]c2ccccc12
Target:
Mitochondrial Metabolism

References

Lei Q, et al. Mitochonic acid 5 activates the MAPK-ERK-yap signaling pathways to protect mouse microglial BV-2 cells against TNF?-induced apoptosis via increased Bnip3-related mitophagy. Cell Mol Biol Lett. 2018 Apr 5;23:14. Suzuki T, et al. Mitochonic Acid 5 Binds Mitochondria and Ameliorates Renal Tubular and Cardiac Myocyte Damage. J Am Soc Nephrol. 2016 Jul;27(7):1925-32.