TargetMol

DO1

Product Code:
 
TAR-T7857
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7857-5mg5mg£111.00
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Quantity:
TAR-T7857-1mL1 mL * 10 mM (in DMSO)£122.00
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Quantity:
TAR-T7857-10mg10mg£128.00
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Quantity:
TAR-T7857-25mg25mg£153.00
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Quantity:
TAR-T7857-50mg50mg£230.00
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Quantity:
TAR-T7857-100mg100mg£310.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
DO1 is an anti-amyloid agent which potently delays both seeded and non-seeded Aβ42 polymerization at substoichiometric concentrations
CAS:
2581-69-3
Formula:
C18H14N4O2
Molecular Weight:
318.336
Purity:
0.9991
SMILES:
[O-][N+](=O)c1ccc(cc1)N=Nc1ccc(Nc2ccccc2)cc1

References

Boeddrich A, Babila JT, Wiglenda T,et al.The Anti-amyloid Compound DO1 Decreases Plaque Pathology and Neuroinflammation-Related Expression Changes in 5xFAD Transgenic Mice[J].Cell Chem Biol. 2019 Jan 17 ;26(1):109-120.e7.