TargetMol

PF-05175157

Product Code:
 
TAR-T7163
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7163-5mg5mg£119.00
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Quantity:
TAR-T7163-1mL1 mL * 10 mM (in DMSO)£124.00
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Quantity:
TAR-T7163-10mg10mg£148.00
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Quantity:
TAR-T7163-25mg25mg£226.00
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Quantity:
TAR-T7163-50mg50mg£380.00
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Quantity:
TAR-T7163-100mg100mg£547.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
PF 05175157 is an inhibitor of acetyl-CoA carboxylase 1 (ACC1) and ACC2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, respectively
CAS:
1301214-47-0
Formula:
C23H27N5O2
Molecular Weight:
405.502
Pathway:
Metabolism
Purity:
0.9978
SMILES:
CC(C)n1ncc2CC3(CCN(CC3)C(=O)c3ccc4nc(C)[nH]c4c3)CC(=O)c12
Target:
Acetyl-CoA Carboxylase

References

Jim?nez de Oya, Nereida, Esler W P , Huard K , et al. Targeting host metabolism by inhibition of acetyl-Coenzyme A carboxylase reduces flavivirus infection in mouse models[J]. Emerging Microbes & Infections, 2019, 8(1):624-636.