TargetMol

Ombitasvir

Product Code:
 
TAR-T7158
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7158-1mg1mg£98.00
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TAR-T7158-5mg5mg£132.00
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TAR-T7158-1mL1 mL * 10 mM (in DMSO)£169.00
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TAR-T7158-10mg10mg£172.00
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TAR-T7158-25mg25mg£263.00
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TAR-T7158-50mg50mg£418.00
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TAR-T7158-100mg100mg£583.00
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TAR-T7158-500mg500mg£1,171.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Ombitasvir is an orally bioavailable and potent inhibitor of the hepatitis C virus (HCV) non-structural protein 5A (NS5A).with EC50s of 0.82 to 19.3 pM against HCV genotypes 1 to 5, and 366 pM against genotype 6a
CAS:
1258226-87-7
Formula:
C50H67N7O8
Molecular Weight:
894.127
Pathway:
Microbiology/Virology; Proteases/Proteasome
Purity:
0.9956
SMILES:
COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)Nc1ccc(cc1)[C@@H]1CC[C@H](N1c1ccc(cc1)C(C)(C)C)c1ccc(NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)OC)C(C)C)cc1
Target:
HCV Protease

References

Krishnan P, Beyer J, Mistry N,et al.in vitro and in vivo antiviral activity and resistance profile of ombitasvir, an inhibitor of hepatitis c virus ns5a[J].Antimicrob Agents Chemother. 2015 Feb;59(2):979-87. Keating, Gillian M . Ombitasvir/Paritaprevir/Ritonavir: A Review in Chronic HCV Genotype 4 Infection[J]. Drugs, 2016, 76(12):1203-1211.