TargetMol

SU 5402

Product Code:
 
TAR-T6996
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6996-5mg5mg£118.00
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Quantity:
TAR-T6996-1mL1 mL * 10 mM (in DMSO)£123.00
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Quantity:
TAR-T6996-10mg10mg£145.00
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Quantity:
TAR-T6996-25mg25mg£206.00
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Quantity:
TAR-T6996-50mg50mg£298.00
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Quantity:
TAR-T6996-100mg100mg£436.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
SU5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.
CAS:
215543-92-3
Formula:
C17H16N2O3
Molecular Weight:
296.326
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis
Purity:
0.9964
SMILES:
Cc1c[nH]c(C=C2/C(=O)Nc3ccccc23)c1CCC(O)=O
Target:
VEGFR; FGFR; PDGFR

References

Trzci?ska-Daneluti AM, et al. RNA Interference Screen to Identify Kinases That Suppress Rescue of ?F508-CFTR. Mol Cell Proteomics. 2015 Jun;14(6):1569-83. Lo AK, et al. J Pathol. 2015. doi: 10.12002/path.4575. Fong TA, et al. Cancer Res. 1999, 59(1), 99-106. Sun L, et al. J Med Chem. 1999, 42(25), 5120-5130. Li Y, et al. Calcif Tissue Int. 2013, 93(6), 556-5 64.