TargetMol

Hydroxy-Dynasore

Product Code:
 
TAR-T6822
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
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CodeSizePrice
TAR-T6822-5mg5mg£107.00
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Quantity:
TAR-T6822-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T6822-10mg10mg£132.00
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Quantity:
TAR-T6822-25mg25mg£182.00
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Quantity:
TAR-T6822-50mg50mg£258.00
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Quantity:
TAR-T6822-100mg100mg£349.00
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Quantity:
TAR-T6822-200mg200mg£485.00
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Quantity:
TAR-T6822-500mg500mg£733.00
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Quantity:
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Further Information

Bioactivity:
Dyngo-4a , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM, respectively.
CAS:
1256493-34-1
Formula:
C18H14N2O5
Molecular Weight:
338.319
Pathway:
Cytoskeletal Signaling
Purity:
0.98
SMILES:
Oc1cc(O)c(C=NNC(=O)c2cc3ccccc3cc2O)cc1O
Target:
Dynamin

References

. Dyngo-4a protects mice from rotavirus infection by affecting the formation of dynamin 2 oligomers. Science Bulletin. 2020 Gagliardi M, et al. J Cell Sci. 2014, 127(22), 4918-4926. Quanzhi Zhang 1,a,b, Qiuhan Zhang 1,b, Zhichao Xu c, Qi Tang b, Xinjin Liu b, Danping Niu b, Xiaoming Gao a, Ke Lan b,*, Shuwen Wu. Dyngo-4a protects mice from rotavirus infection by affecting the formation of dynamin 2 oligomers. Science Bulletin. 2020 McCluskey A, et al. Traffic. 2013, 14(12), 1272-1289. Harper CB, et al. J Biol Chem. 2011, 286(41), 35966-35976.