TargetMol

KPT276

Product Code:
 
TAR-T6074
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6074-5mg5mg£109.00
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TAR-T6074-10mg10mg£124.00
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TAR-T6074-1mL1 mL * 10 mM (in DMSO)£125.00
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TAR-T6074-25mg25mg£168.00
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TAR-T6074-50mg50mg£213.00
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This product comes from: United States.
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Further Information

Bioactivity:
KPT-276 is an orally bioavailable selective inhibitor of nuclear export (SINE) that irreversibly bind to CRM1 and block the function of CRM1.
CAS:
1421919-75-6
Formula:
C16H10F8N4O
Molecular Weight:
426.27
Pathway:
Membrane transporter/Ion channel
Purity:
1
SMILES:
FC(F)(F)c1cc(cc(c1)C(F)(F)F)-c1ncn(C=C/C(=O)N2CC(F)(F)C2)n1
Target:
CRM1

References

Ranganathan P, et al. Blood. 2012, 120(9), 1765-1773. Schmidt J, et al. Leukemia. 2013, 27(12), 2357-2365. Azmi AS, et al. Exp Hematol. 2013, 41(1), 67-78.