TargetMol

Sertindole

Product Code:
 
TAR-T5858
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5858-5mg5mg£107.00
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Quantity:
TAR-T5858-1mL1 mL * 10 mM (in DMSO)£109.00
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TAR-T5858-10mg10mg£118.00
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TAR-T5858-25mg25mg£188.00
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TAR-T5858-50mg50mg£303.00
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TAR-T5858-100mg100mg£388.00
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This product comes from: United States.
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Further Information

Bioactivity:
Sertindole is an atypical antipsychotic that binds to dopamine D2 receptors and the serotonin (5-HT) receptor subtypes 5-HT1D, 5-HT2A, and 5-HT2C (Kds = 2.7, 20, 0.14, and 6 nM, respectively)
CAS:
106516-24-9
Formula:
C24H26ClFN4O
Molecular Weight:
440.95
Pathway:
Neuroscience; GPCR/G Protein; Autophagy
Purity:
0.9974
SMILES:
Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12
Target:
Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; Autophagy

References

Nikiforuk A , Popik P . Effects of quetiapine and sertindole on subchronic ketamine-induced deficits in attentional set-shifting in rats[J]. Psychopharmacology, 2012, 220(1):65-74. M?Rk A , Witten L M , Arnt J . Effect of sertindole on extracellular dopamine, acetylcholine, and glutamate in the medial prefrontal cortex of conscious rats: a comparison with risperidone and exploration of mechanisms involved[J]. Psychopharmacology, 2009, 206(1):39-49. Idris N , Neill J , Grayson B , et al. Sertindole improves sub-chronic PCP-induced reversal learning and episodic memory deficits in rodents: involvement of 5-HT6and 5-HT2Areceptor mechanisms[J]. Psychopharmacology, 2010, 208(1):23-36.