TargetMol

Benzamil

Product Code:
 
TAR-T5850
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T5850-5mg5mg£111.00
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TAR-T5850-10mg10mg£119.00
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TAR-T5850-1mL1 mL * 10 mM (in DMSO)£129.00
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TAR-T5850-25mg25mg£172.00
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TAR-T5850-50mg50mg£262.00
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TAR-T5850-100mg100mg£417.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Benzamil is an epithelial sodium channel (ENaC) blocker that inhibits sodium transport from (IC50 = 4 nM) and binds to (Kd = 5 nM) bovine kidney cortex membrane vesicles.
CAS:
2898-76-2
Formula:
C13H14ClN7O
Molecular Weight:
319.75
Pathway:
Membrane transporter/Ion channel
Purity:
0.993
SMILES:
Nc1nc(N)c(nc1Cl)C(=O)NC(=N)NCc1ccccc1
Target:
Na+/Ca2+ Exchanger; Sodium Channel

References

Nishimura M , Ohtsuka K , Nanbu A , et al. Benzamil blockade of brain Na+ channels averts Na(+)-induced hypertension in rats.[J]. American Journal of Physiology, 1998, 274(2):635-44. Jeong S , Lee S H , Kim Y O , et al. Antinociceptive Effects of Amiloride and Benzamil in Neuropathic Pain Model Rats[J]. Journal of Korean Medical Science, 2013, 28(8).