TargetMol

QX77

Product Code:
 
TAR-T4663
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4663-1mg1mg£95.00
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Quantity:
TAR-T4663-5mg5mg£128.00
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Quantity:
TAR-T4663-1mL1 mL * 10 mM (in DMSO)£134.00
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TAR-T4663-10mg10mg£168.00
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Quantity:
TAR-T4663-25mg25mg£249.00
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Quantity:
TAR-T4663-50mg50mg£367.00
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Quantity:
TAR-T4663-100mg100mg£511.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
QX77 is a chaperone-mediated autophagy (CMA) activator.
CAS:
1798331-92-6
Formula:
C16H13ClN2O2
Molecular Weight:
300.74
Pathway:
Autophagy;
Purity:
0.9792
SMILES:
CC(=O)Nc1ccc(cc1)C1=Nc2ccc(Cl)cc2OC1
Target:
Autophagy

References

Zhang J, et al. Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A. J Biol Chem. 2017 Jun 23;292(25):10328-10346 Liu C, Sun W, Zhu T, et al. Glia maturation factor-? induces ferroptosis by impairing chaperone-mediated autophagic degradation of ACSL4 in early diabetic retinopathy. Redox Biology. 2022: 102292.