TargetMol

Edoxudine

Product Code:
 
TAR-T4374
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4374-1mL1 mL * 10 mM (in DMSO)£96.00
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TAR-T4374-10mg10mg£107.00
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TAR-T4374-25mg25mg£133.00
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TAR-T4374-50mg50mg£164.00
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TAR-T4374-100mg100mg£229.00
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This product comes from: United States.
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Further Information

Bioactivity:
Edoxudine, an antiviral drug, is an analogue of thymidine and shows effectiveness against the herpes simplex virus. Edoxudine is used as a 5-fluorouracil (FU) modulator. Edoxudine may be used to enhance the therapeutic index of 5-FU by reducing the catabolism, prolonging the plasma and intratumoral concentrations of 5-FU, and offering protection to normal organs by increasing the endogenous uridine levels. It can also enhance the antitumour action of 5-FU.
CAS:
15176-29-1
Formula:
C11H16N2O5
Molecular Weight:
256.258
Pathway:
Immunology/Inflammation; Microbiology/Virology
Purity:
1
SMILES:
CCc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O
Target:
Antiviral; Antibacterial

References

Jeney A, et al. 5-Ethyl-2'-deoxyuridine: an explanation for its lack of cytotoxic action in vivo[J]. European Journal of Cancer & Clinical Oncology, 1986, 22(5):557-562. Kralovanszky, et al. 5-Ethyl-2'-deoxyuridine, a modulator of both antitumour action and pharmacokinetics of 5-fluorouracil[J]. Journal of Cancer Research & Clinical Oncology, 1999, 125(12):675-684.