TargetMol

NCGC00029283

Product Code:
 
TAR-T40823
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T40823-1mg1mg£197.00
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TAR-T40823-1mL1 mL * 10 mM (in DMSO)£386.00
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TAR-T40823-5mg5mg£389.00
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TAR-T40823-10mg10mg£544.00
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TAR-T40823-25mg25mg£830.00
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TAR-T40823-50mg50mg£1,099.00
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Quantity:
TAR-T40823-100mg100mg£1,460.00
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Further Information

Bioactivity:
NCGC00029283 is a werner syndrome helicase-nuclease (WRN) helicase inhibitor with IC 50 s of 2.3 μM, 12.5 μM, and 3.4 μM for WRN, BLM and FANCJ helicase, respectively.
CAS:
714240-31-0
Formula:
C18H12FN3O3
Molecular Weight:
337.31
Pathway:
Cell Cycle/Checkpoint|DNA Damage/DNA Repair
Purity:
0.98
SMILES:
COc1ccc2[nH]c(=O)c(cc2c1)-c1noc(n1)-c1ccc(F)cc1
Target:
DNA/RNA Synthesis

References

Joshua A Sommers, et al. A high-throughput screen to identify novel small molecule inhibitors of the Werner Syndrome Helicase-Nuclease (WRN). PLoS One. 2019 Jan 9;14(1):e0210525.