TargetMol

Eflornithine

Product Code:
 
TAR-T40811
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T40811-100mg100mgEnquire
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TAR-T40811-50mg50mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Eflornithine is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase . Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.
CAS:
70052-12-9
Formula:
C6H12F2N2O2
Molecular Weight:
182.171
Purity:
0.98
SMILES:
NCCCC(N)(C(F)F)C(O)=O

References

Mastrodomenico V, LoMascolo N J, Firpo M R, et al.Persistent Coxsackievirus B3 Infection in Pancreatic Ductal Cells In Vitro Downregulates Cellular Polyamine Metabolism.Msphere.2023: e00036-23. Kumar A, et al. A method to improve the efficacy of topical eflornithine hydrochloride cream. Drug Deliv. 2016 Jun;23(5):1495-501. Burri C, et al. Eflornithine for the treatment of human African trypanosomiasis. Parasitol Res. 2003 Jun;90 Supp 1:S49-52. Balfour JA, et al. Topical eflornithine. Am J Clin Dermatol. 2001;2(3):197-201; discussion 202. Lipke DW, et al. Eflornithine alters changes in vascular responsiveness associated with coarctation hypertension. Clin Exp Hypertens. 1997 Apr;19(3):297-312.